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I expect Netflix, like all businesses, and in particular all businesses in relatively new industries, to change as it learns the difference between short-term and long-term effects. Chasing short-term growth metrics while you're a growing company makes sense and I would expect nothing different. Then you stabilize, you run out of new customers (not literally but in terms of the exponential growth stuff), and you have to downshift and figure out what people want a bit more. I think that'll happen, and I expect a sort of second renaissance of good Netflix shows, more on par with what we saw early on.
We'll see, though.
As for things I'm really sad they canceled...Santa Clarita Diet would have to be the #1 choice. That one really grew on me and its mythology was getting pretty zany by the end, too. One or two more seasons of that would've been lovely.
After that, it's hard to get too riled up about any of them, most of their biggest hits are, in fact, their better shows, and those are the ones they usually keep around. I guess I'm annoyed (and a little surprised) they keep small, cheap things like The Joel McHale Show around. I would say American Vandal, too, but I suspect that had as much to do without the creators' interest in doing something else. I thought Daredevil was pretty solid, too, and would've liked more of that.