I think the first time I really took notice of Mulholland Drive was when I saw the diner scene on a "scariest movie scenes ever" list (think it was top 3 along with the shower scene from Psycho and the last scene of Carrie - can't remember the exact order, though) so I watched the embedded YouTube clip and even that was enough to freak me out (much less watching it properly on a larger screen) so I couldn't deny its high ranking. Not entirely sure if Eraserhead quite matches that, but it comes close enough and - more importantly - consistently maintains that sense of dread in a way that isn't off-set by the kind of humour or beauty or whatever else that characterises your "average" Lynch film.
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Iro's Top 100 Movies v3.0
I really just want you all angry and confused the whole time.